Amfepramone

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Amfepramone inhibits the feeling of hunger, reduces the need for sleep, and acts stimulating. Amfepramone belongs to the Group of amphetamines and is used in medicine as an appetite suppressant in diet-induced obesity. Diethylpropion is a controversial substance. The drug was withdrawn from the market in Europe by withdrawal of authorisations in June 2001. Since 2003, it is however available as a prescription drug in Germany.

Effect:

In the active state, the performance is increased. The heart activity is increased, the bloodcirculation and blood pressure are increased. This results in wide awakeness. Tiredness, sleep, and the feeling of hunger are suppressed.

Diethylpropion is an indirect sympathomimetic. It increases the number of messengers that are required for signal transmission in the sympathetic nervous system. It is assumed that a direct inhibitory effect on the appetite-regulating center of the brain comes from Amfepramone.

Diethylpropion is used for appetite suppression in athletes and bodybuilding circles. It also features a booster, but is not an alternative to ephedrine, because the side effects of Amfrepramon are too strong.

Important with the use of amfepramone is at a long-term treatment or in large doses, the body can get used to the drug and can be dependent on the drug.

Amfepramone should be applied usually only 4-6, weeks, maximum 12 weeks. Amfepramone should only be used in very overweight (BMI greater than 30) or when low-calorie diet, changes in eating habits and exercise had not the desired weight-reducing effect.

Areas of application:

Overweight (obesity, obesity)

Side effects:

Tendency to seizures, cardiac arrhythmia, heart palpitations, increase in blood pressure, restlessness, anxiety, urinary urgency, Central excitation, mental alterations, tremor of the hands, Central and myogenic tachycardia, increase in blood pressure, gallop, heart palpitations, insomnia, fever, illusionary misjudgements, optical and acoustic hallucinations, spasms, hyperthermia, heart and circulatory collapse, respiratory paralysis, death increased perception and mood problems, such as depression, euphoria, disorders, hallucinations and nightmares.

In long term treatment and in high doses, one can get their body on the drug and become dependent on the medicine. After long and high-dose use it can cause sudden weaning withdrawal symptoms. The drug is for short-term use only.

Amfepramone should be applied usually only 4-6, weeks, maximum 12 weeks. The application is prescribed usually only from an overweight (BMI greater than 30) and if the following therapeutic measures such as changes in eating habits, switching to low-calorie diet and exercise have no effect.

Interactions:

The need for blood sugar-lowering drugs such as insulin may be affected. In combination with blood clotting inhibitors, the issue of bleeding is increased. While using cold – cold and asthma medications that also contain active ingredients in the drug group of sympathomimetic drugs, and at high doses can caffeine, to increase the side effects.

Doping information:

Amfepramone belongs to the Group of amphetamines, is a doping substances banned by the IOC and can of Thin film and paper chromatography, UV absorption spectroscopy and IR absorption spectrometry detected.

Dosage / application:

in bodybuilding circles capsules at 25 mg diethylpropion day 2-3 are accessible.

The dosage information here are not recommendations by medical advice. It’s information used by bodybuilders who use r have used these drugs. The dosages are never as generally valid. If you have the intention to use steroids or similar products, ask a doctor or pharmacist.

Blackmarket / availability:

60 capsules of à 25mg active substance Amfepramone cost on the black market between 60-90 euros. The availability is moderate. Alternatively, Amfepramone in Germany can be drawn as a prescripted medication in the pharmacy.

Synonyme:

Amfepramonum, Amfepramon, Amfepramone hydrochloride, Amfepramonhydrochlorid, Diethylpropione

Handelsnamen / Hersteller:

Regenon / Temmler Pharma GmbH & Co. KG (Deutschland)
Tenuate Retard Retardtabletten / Artegodan GmbH (Deutschland)
Apisate / Wyeth (Großbritanien)
Anorex / Crinex (Frankreich)
Atractil / Trenker (Belgien)
Bonumin / Medipolar (Finland)
Delgamer / Marion Merrell (Spanien)
Dobesin / Abigo (Dänemark)
Linea / Valeas (Griechenland)
Frekentine /

Chemische Informationen:Amfepramon Amfepramone - Molekularformel

Molekular formula: C13H19NO
Molekula weight: 205.296 g/mol
Mono-isotopic mass: 205.146667 Da
Half life: 4 – 6 Stunden
Meltingpoint: 175 °C

ATC-Code‎: ‎A08AA03
CAS: 90-84-6

The melting point of diethylpropion hydrochloride is: 168 ° C (decomposition). The molecular weight is 241.76 g / mol.

Texture: Fine, off-white, crystalline powder with a slightly bitter taste; soluble in water, alcohol and chloroform, insoluble in ether.

2-(Diethylamino)-1-phenyl-1-propanon
2-diethylamino-1-phenyl-propan-1-one, 2-Diethylaminopropiophenon, 1-Phenyl-2-diethylamino-1-propanon, Diethylpropion, a-Benzoyl-triethylamin, 2-(Diethylamino)-1-phenyl-1-propanon