This Post is also available in: German
Dutasteride is a 5α-reductase inhibitor which interferes with the hormonal metabolism of the sex hormone testosterone in dihydrotestosterone (DHT).
It does not push your strength and is used in doping as a masking agent to prevent the detection of anabolic steroide abuse.
It is used in medicine for the treatment of benign prostate hyperplasia (BPH – a benign prostate enlargement with moderate to severe complaints). Specifically, the conversion of testosterone into dihydrotestosterone is to be inhibited to thereby reduce an enlarged prostate. Dutasteride is also effective for the treatment of androgenetic alopecia (hair loss) but is not permitted in Germany.
Some bodybuilders use it to counter the hair loss caused by AAS.
Dutasteride is available in Germany only with a prescription.
Dutasteride is used to mask anabolic use. It is on the doping list and is therefore forbidden.
(Including chest enlargement and / or painful chest compressions). Allergic reactions like skin rash, itching or hives, swelling of the face, lips,
The side effects can occur up to 6 months after termination of the therapy because of the very long plasma seawage time of 5 weeks. There are also reports of permanent damage after discontinuation of the drug, similar to the related finasteride.
Application / Dosage:
To mask AAS, bodybuilders often use 0.5mg of dutasteride per day. Medicine with this ingredient must not be used by women, children and adolescents or persons with hepatic impairment or 5α-reductase inhibitors.
Black market prices / availability:
Dutasteride can be obtained with prescription via the pharmacy and costs per tablet with 0.5mg of active substance Dutasteride ca 1.50 euros. It is usually available in pack sizes of 90 tablets.
Dutasteride, Dutasteridum (Latin), Dutasterida (Spanish)
Trade Name / Manufacturer:
Avodart / GlaxoSmithKline (GSK)
Dutas / Dr Reddy’s
Duprost / Cipla
Duagen / Demo, Greece
Duagen / GlaxoSmithKline, Italy
Duagen / Dutasteride and Tamsulosin, Etex, Chile
Deratos / Regiomedica, Netherlands
Dudat / Sai Mirra, Myanmar
Dutamed / Cande s.r.o., Slovakai
Dutapros / Koçak, Turkey
Dutagen / Ranbaxy
Duodart / GlaxoSmithKline (GSK)
Molecular formula: C27H30F6N2O2
Molecular weight: 528.539 g / mol
Monoisotopic mass: 528,221 g / mol
Plasma half-life: approx. 5 weeks
(5α, 17β) -N- (2,5-bis (trifluoromethyl) phenyl) -3-oxo-4-azaandrost-1-en-17-carboxamide
(4aR, 4bS, 6aS, 7S, 9aS, 9bS, 11aR) -N- [2,5-bis (trifluoromethyl) phenyl] -4a, 6a-dimethyl-2-oxo-2,4a, 4b, 6a, 7,8,9,9a, 9b, 10,11,11a-tetradecahydro-1H-indeno [5,4-f] quinoline-7-carboxamide