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In medicine, phosphatidylserine isĀ used to support the treatment of dementia and hyperactivity.
The use of phosphatidylserine is intended to improve the cognitive performance in the elderly, as well as to alleviate depression and, in the case of athletes, keep the frequently increased cortisone values low after a workout. An improved performance of the short-term memory as well as the concentration is noted in most studies.
A common dosage for improving the ability to concentrate and counteract depression is 100 mg per day.

Several studies have shown that the phosphatidylserine can increase its ability to concentrate. Bodybuilders and athletes have discovered phosphatidylserine due to its ability to lower cortisol levels. A decreased cortisone value reduces the anticatabolic (tissue-degrading) effects caused by hard training or persistence training. Not only doping bodybuilders and prohormone consumers, but also natural bodybuilders use phosphatidylserine products.

Side effects:

No long-term studies are available. Previously, phosphatidylserine products were partly derived from bovine cereal, which was a risk of BSE infection.
Most phosphatidylserine preparations are now made from soybeans.

Application / Dosage:

In bodybuilding frequently to be met is a dosage of 2x daily 400 mg each phosphatidylserin. The first dose usually takes place in the morning about 30 minutes before the meal, the second dose about 30 minutes before the workout. A cure usually lasts for 8 – 12 weeks, followed by a break for 4 – 8 weeks.

The dosage information given here is not intended as a dosage recommendation or medical advice. These are statements by bodybuilders who have used or used these active ingredients. The dosages should never be regarded as generally valid. If you are using the idea of using steroids or similar, ask a doctor or pharmacist.

Black market prices / availability:

Phosphatidyl serine preparations are prescription free and cost between 0.50 – 1.80 euros per capsule with 300mg of active substance.


Phosphatidyl products are now increasingly falsified.


Phosphatidylserine, phosphatidylserine, phosphate idyl serine, phosphatidyl serine

Trade Name / Manufacturer:

Phosphatidyl serine capsules / Espara GmbH
Phosphatidyl-serine / VitaBVasix
IQ-Energy / Alpinamed
C3 – cortisone blocker / EAS
SerinAid / CHEMI Nutra
Neuro-PS / ViaBiona

Chemical information:Phosphatidylserin - Phosphatidylserine - Molekularformel

Molecular Formula: C13H24NO10P
Molecular weight: 385,304 g / mol
Monoisotopic mass: 385.113770 Da

(2S) -2-amino-3 – [(2-butanoyloxy-3-propanoyloxy-propoxy) hydroxy-phosphoryl] oxy-propanoic acid
(2S) -2-amino-3 – [[(2R) -2-butanoyloxy-3-propanoyloxypropoxy] hydroxyphos
Phoryl] oxypropanoic acid
1,2-diacyl-sn-glycerol 3-phospho-L-serine, (2S) -2-amino-3 – [[2R) -2-butanoyloxy-3-propanoyloxypropoxy] hydroxyphosphoryl oxypropanoic acid
O – {[(2R) -2- (butyryloxy) -3- (propionyloxy) propoxy] (hydroxy) phosphoryl} -L-serine

Keywords: phosphatidilserin, Phosphatydil serine, Phosphatydil-Serine, Phosphatidyl-Serine, Phosphatidyl Serine, Phosphatidly-serine