Pizotifen

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Pizotifen is a serotonin antagonist (5-HT2B receptor antagonist). It belongs to the group of appetite stimulants and is used in medicine to increase appetite and prevent cluster headache, vasomotor headache and migraine. Pizotifen does not help if you suffer of headache it only may help to prevent. The usual dosages range from 0.5mg per day to 4.5mg per day spread over 3 intekes. In Germany it was known under the brand names Mosegor and Sandomigran. It has been withdrawn from the market and is only available through the international pharmacy.

In bodybuilding, pimzotifen is used to increase appetite, since a steroid cure without the right diet and training methods would only result in little success.
Since bodybuilders often do not have enough appetite during a steroid treatment and therefore have to force themselves to eat, pimpotifen is a popular means to arouse hunger.
Tests over several years in rats and dogs resulted in damage to the liver and the thyroid gland.

Effects:

Appetizing, mood-enhancing

Side effects:

Dizziness, fatigue, constipation, drowsiness, can cause sleepiness, since pimpotifen usually tired, is a consumption before going to bed.

Application / dosage:

Bodybuilders and athletes often use a dosage of 0.5mg of active ingredient pimpotifen per day for the duration of their steroid cure.

Pizotife preparations are sold in two versions. Once there is the pure Pizotifen, then also Pizotifen Malate is available. The effect is the same for both preparations.
The dosage should be observed, which corresponds to 0.725mg Pizotifen Malate 0.5mg pure pizzotifen. 2,175mg Pizotifen Malate corresponds to a 1.5mg pizotifen tablet.

Overdose may cause: spasm, nausea, vomiting, low blood pressure, coma

The dosage information given here is not intended as a dosage recommendation or medical advice. These are statements by bodybuilders who have used or used these active ingredients. The dosages should never be regarded as generally valid. If you are using the idea of using steroids or similar, ask a doctor or pharmacist.

Black market prices / availability:

A pack of 30 tablets of 0.5mg of active ingredient Pizomifene costs between 6 and 9 euros on the black market. This corresponds to a tablet price of 0.20 – 0.30 Euro per piece.

Also available is Pizotifen in liquid form. Syrup containing 0.5 mg of active ingredient pomomifene per 10 ml of liquid is available from ASIA Pharmaceutical.

Counterfeits:

No counterfeits are known.

Synonyms:

Pizotifenum, Pizotifeni Hydrogenomaleas, Pizotifen Malate, Pizotyline (USAN), Pizotifen Hydrogen Malate, Pizotifene

Trade Name / Manufacturer:

Mosegor / Novartis
Sandomigran / Novartis
Anorsia / Asian Pharm (Thailand)
Litec / Novarts (Philippines)
Lysagor / Kalbe (Indonesia)
Moselar / Milano (Thailand)
Pizomed / Medifive (Thailand)
Polomigran / Polon (Poland)
Sandomigran / Paladin (Canada)
Sandomigrin / Novartis (Scandinavia, Norway, Sweden, Denmark)
Sandomiran, Sanmigran, Sanomigran,
Mafen / Pharmaland (Thailand)
Appetens / Novartis (Philippines)
Mosegor Vita / Hiking (Philippines)

Chemical information:Pizotifen - Pizotifene - Molekuarformel

Molecular formula: C19H21NS
Molecular weight: 295,442 g / mol
Monoisotopic mass: 295.139465 Da
Half-life: 23 hours

IUPAC Name: 4- (1-methyl-4-piperidylidines) -9,10-dihydro-4H-benzo [4,5] cyclohepta [1,2] -thiophene
CAS number: 15574-96-6

Pizotifen must not be exposed to temperatures above 30 degrees Celsius. It must be protected against light and dry.

4- (9,10-dihydro-4 H -benzo [4,5] cyclohepta [1,2-b] thiophen-4-ylidene) -1-methylpiperidine
4- (9,10-dihydro-1-thia-benzo [f] azulen-4-ylidenes) -1-methyl-piperidine (compound with 2-hydroxy-succinic acid)